Regardless of whether the scale of it is being exaggerated or not, I don't think you quite grasp what it feels like to lose control of your body for reasons unknown.
I'm male, and I was spiked at a student halls party - "only" alcohol. I was apparently getting on rather too well with a girl the host of the party had been trying to get off with (I had no designs on her at all but she was funny and had a cool hat), so whilst I was off pontificating away, he was apparently topping my drink up with vodka whenever I wasn't looking. Predictably I got utterly shitfaced in a way I didn't even think was possible, threw up all over the shop and passed out (I was banned from the halls as a result). The people I went to the party with thought this was funny (they saw it happening and didn't tell me until the day after when I asked what the fucking fuck happened) and I could never forgive them for it. Boys will be boys, eh?
About a year later, a female friend of mine was spiked at a club with what they think was rohypnol (I wasn't present for this one, only heard it second hand). She couldn't drink alcohol so was always just on coke or whatever, then started being all woozy. Told the friends she was with that something was fucking her up before she basically passed out. She'd been sexually assaulted before (pre-uni, through spiking via booze in her drink) so, to put it crudely, knew the drill. She was lucky this time, as was the assailant who made themselves scarce. Her boyfriend was the sort of fella who wouldn't hurt a fly, but who moved in circles that would take a... dim view of anyone engaging in this sort of behaviour.
Friends shouldn't let friend's drinks go unattended or unwatched, end of. Spiking isn't fun regardless of gender, age or scale and even if no other assault happens as a result it can leave serious psychological scars. Spiking happens because the world is full of cunts. It sucks that we have to look out for it, but everyone should be looking out for it even if it's only a statistical rarity.