In the wide-ranging Telegraph interview to mark the prime minister's first year in office, Boris Johnson insisted his agenda for domestic reform and "levelling up" the economy would not be blown off course by the pandemic.
"We want to be a transformative government because there's a massive opportunity in this country to do things differently and to do things better," he said.
"We've seen that really exemplified in what happened with coronavirus."
He said that while the Civil Service was "absolutely fantastic", lessons could be learned from the pandemic.
"Maybe there are ways in which we can all learn together to do things faster, to have a real spirit of 'can do'. I think sometimes it's a question of confidence and belief," he said.