Urban75 Home About Offline BrixtonBuzz Contact

Possible vaccines/treatment(s) for Coronavirus

A pretty good reality check regarding stuff like how many people need vaccinating before things like population immunity and utter normality become relevant.


Good corrective read ( :( )..

But I hope there aren't too many people overall -- at least, not on Urban!! -- hoping for population-level immunity or complete normality in short order.

But I do tend to think that in the context of at least the UK and Western countries ( :( ), there'll be significant improvements as 2021 gets on.
That is, as more and more vaccine doses get acquired and distributed and given.

I am aware of two doses being needed, and of people needing a few weeks before two doses of a vaccine kick in properly.

I am though really hoping that the Oxford/AstraZeneca vaccine gets approved soon.
I believe that the MHRA are focussing on that right now, and that a peer-reviewed Lancet article is in the pipline too.
Emergency MHRA approval in early New Year, or even before Xmas, has been suggested?

I wish for approval of this hugely important extra vaccine a lot (obviously without any risk of rushing, or of cutting any corners, obvs!).

Not least because the UK Government has ordered 100 million doses (?) of Oxford/AZ,, and it won't need deep-freeze storage in the way that Pfizer/BioNTech's vaccine and Moderna's vaccine will.

If I recollect '100 million' rightly, for Oxford/AZ -- that's a LOT of doses!

So some earlier talk of exceptionally long delays, just might turn out overdone.
ETA -- by which I mean no real effect of the vaccination programme until very late 2021 or 2022** -- that would be depressing (although earlier this year, before vaccines began to materialise at all, late 2021 or 2022 could easily have been seen to be on the optimistic side?!)

**I don't think the BBC article was suggesting those dates about the UK at least, anyway. It was correctly trying to take a broader, more world-wide perspective (that's how I read it , anyway).
 
Last edited:
(Right! I don't think I need any more edits and corrections to the above post now! I'm sober, but I typoed a load of mistakes and left out stuff in the first version :oops: )
 
Just a minor aside on vaccines: I had my flu jab today as part of the 50-64 year old group, after getting a text from my GP saying to book it a week ago. When I got there, there was a queue of maybe 30 people outside, along with another dozen inside the waiting room. Turned out they were using one GP practice to process patients from 2 practices. No problem with that though the social distancing was a bit lax in places. What I did find significant was that a practice nurse was going up and down the queue telling people that the vaccine being used (Flublok) was unlicensed in this country though it is licensed in the U.S and is under emergency license here. I had a minor :hmm: at the point, but went on to have it, assuming there would have been enough checks of one sort or another.

Reason I mention this is I can see the logic of only telling patients at the point they are in the queue as a logistics issue, maximising the number accepting the vaccine whilst avoiding the practice having to spend time in dialogue with patients. But it's really not a good look and probably doesn't help the mindset of anybody who might be a bit twitchy about accepting the covid vaccine. If you really want to build trust you need a mature and open discussion between government, health professionals and the public.

p.s. I've just checked and there were media reports about Flublok getting a temporary licence a few weeks ago. I think the point still stands though about having an actual open, mature discussion. There's going to be a real issue about covid vaccine refuseniks, right to the point where it will make herd immunity more difficult to achieve.
 
Wilf I had a text offering me a flue jab just yesterday, I am 56 but I haven't ever had a jab so far. I didn't think I would bother, never had the flue. Is that irresponsible?
 
Wilf I had a text offering me a flue jab just yesterday, I am 56 but I haven't ever had a jab so far. I didn't think I would bother, never had the flue. Is that irresponsible?
Dunno really, I'd think about it purely in terms of self interest. Getting flu in conjunction with Covid isn't a very inviting prospect.
 
Those are speculation though. If they do come into be, maybe they will create exemptions that can be issued by dr / consultant. I don’t know, none of us do.
I can't get live vaccines and when I went to somewhere where I might need a yellow fever certificate*, my consultant wrote a letter explaining why I couldn't get it. Seemed to be a pretty standard thing so assume something similar would apply for this for if people can't be vaccinated for medical reasons.

*It's only an issue in certain parts of that country -- where I wasn't going to -- but sometimes they apparently ask for it when you arrive on international flights to the capital city, even though it's not in a yellow fever area.
 
Wilf I had a text offering me a flue jab just yesterday, I am 56 but I haven't ever had a jab so far. I didn't think I would bother, never had the flue. Is that irresponsible?

I am having a flu jab as part of the over 50's programme this year, the thought of being unlucky and getting both flu & covid at the same time is enough to motivate me, as there would be a massive increased risk of serious illness or death.
 
Had the flu jab way back (end of Sept) now I'm hoping for the covid one as soon as they get down to my age group.
Not helped by our local area now having a fairly serious spike in the case rate [over 400 / 100k] - although, not in absolute / actual case numbers.
Unless I can sneak one slightly early as a) the rest of my household are all over 65, and b) with some health issues of mine (principally stupidly low blood pressure and a peculiar digestive system - but neither of those are likely to help push me up the list !)
The other alternative is grabbing a refusenik's ( or someone much older, who's died recently) doses to save wastage [which wouldn't apply to the Oxford vax] ...
 
The other alternative is grabbing a refusenik's ( or someone much older, who's died recently) doses to save wastage [which wouldn't apply to the Oxford vax] ...

I doubt that the system is actually going to be setup to enable that option. Bit too early to tell but I dont really see how that would work, especially since they wont be expecting 100% uptake in any target group in the first place.
 
  • Like
Reactions: Sue
Unless I can sneak one slightly early as a) the rest of my household are all over 65, and b) with some health issues of mine (principally stupidly low blood pressure and a peculiar digestive system - but neither of those are likely to help push me up the list !)
The other alternative is grabbing a refusenik's ( or someone much older, who's died recently) doses to save wastage [which wouldn't apply to the Oxford vax] ...

I doubt that the system is actually going to be setup to enable that option. Bit too early to tell but I dont really see how that would work, especially since they wont be expecting 100% uptake in any target group in the first place.
And TBF, it shouldn't work. They're prioritising groups of people for good reasons. Trying to queue jump -- because essentially that's what you seem to be saying -- is shit.
 
And TBF, it shouldn't work. They're prioritising groups of people for good reasons. Trying to queue jump -- because essentially that's what you seem to be saying -- is shit.
There's a reason - I live with three older people, including my OH who does have health issues and one of the other two is months away from their 70th
Also. I'm already over 64, and it is only a matter of a few months before I get to 65 (and close enough that they were happy to do the flu jab) ...

If I was years younger I wouldn't be worried about waiting in the queue ...
 
Between 20 and 35% saying they might not take the vaccine, depending on the question asked:
One in three ‘unlikely to take Covid vaccine’ | Coronavirus | The Guardian
My pure guess is it will be nearer to the lower figure when push comes to shove, but still worrying with regard to achieving 'herd immunity'. As well as refuseniks, there are going to plenty of others who can't take it for medical reasons and a probably larger number who have come off the council tax register, aren't with a GP or are otherwise - shit phrase alert - 'hard to reach'.
 
Herd immunity is absolutely nowhere on my radar with this disease and it would not surprise me if it is never an option that come within a million miles of our reach.

Protecting a percentage of the population who would otherwise be at risk of hospitalisation and death is where my sights are set. Other possibilities exist, but are not something I would want to fill peoples heads with in 2020 or 2021.
 
Between 20 and 35% saying they might not take the vaccine, depending on the question asked:
One in three ‘unlikely to take Covid vaccine’ | Coronavirus | The Guardian
My pure guess is it will be nearer to the lower figure when push comes to shove, but still worrying with regard to achieving 'herd immunity'. As well as refuseniks, there are going to plenty of others who can't take it for medical reasons and a probably larger number who have come off the council tax register, aren't with a GP or are otherwise - shit phrase alert - 'hard to reach'.
I live with a couple of people who have said they won't be getting vaccinated. One works for the NHS (in an admin role) and will change her mind the minute she realises that she might not be able to go abroad without it. The other is more of a loon (she has a cable to her laptop as wifi gives her a headache) but works in retirement housing and will be under some pressure to have it done, I think.
 
Herd immunity is absolutely nowhere on my radar with this disease and it would not surprise me if it is never an option that come within a million miles of our reach.

Protecting a percentage of the population who would otherwise be at risk of hospitalisation and death is where my sights are set. Other possibilities exist, but are not something I would want to fill peoples heads with in 2020 or 2021.
Yeah this.
I’ve had a listen to the indie sage briefing from Friday plus a bbc sounds episode on it & sounded like herd immunity is not remotely on the horizon even if uptake of the vaccines which have positive results is high.
 
Wilf I had a text offering me a flue jab just yesterday, I am 56 but I haven't ever had a jab so far. I didn't think I would bother, never had the flue. Is that irresponsible?

Have the jab weltweit . Why on earth wouldn't you? And having never had the flu is completely irrelevant to the issue. (Except that if you'd had it before you might be keener to have the jab.)
 
I live with a couple of people who have said they won't be getting vaccinated. One works for the NHS (in an admin role) and will change her mind the minute she realises that she might not be able to go abroad without it. The other is more of a loon (she has a cable to her laptop as wifi gives her a headache) but works in retirement housing and will be under some pressure to have it done, I think.

Yeah, I've met a few NHS staff who won't get it, a mix of slight concern through to outright conspiracy bollocks. Wifi headache though, fucking electricity sensitivity nonsense. No wonder she won't get a vaccine the dick.
 
Last edited:
My mother,as i may have mentioned, will have gone once round the clock if she can just survive until 2031 so I aim to push her up the queue as far as proves possible.That said she doesn't work or live in a Care Home so she won't be done in the first wave and,I suppose,won't get the Pfizer jab at all.
I am assuming the procedure is to wait for a call from her GP does anyone know different I wonder?
 
My mother,as i may have mentioned, will have gone once round the clock if she can just survive until 2031 so I aim to push her up the queue as far as proves possible.That said she doesn't work or live in a Care Home so she won't be done in the first wave and,I suppose,won't get the Pfizer jab at all.
I am assuming the procedure is to wait for a call from her GP does anyone know different I wonder?

There hopefully won't be any pushing anyone up the queue. She'll be contacted when she's due it by her GP or similar. Some are being done when people go for appointments (hospital or GP) generally.
 
weltweit - IIRC, the nhs ordered extra flu vax for this winter, to be able to offer the jab to the 50 - 65 year olds.

so, no you are not taking it away from more "deserving cases"

and if you've never had flu you've been lucky, it is a miserable thing to have. Some of the varieties are worse than others.
Getting it and covid together would definitely not be pleasant ...
 
Excellent article -- bigger and better than the good one I posted upthread I think :) -- about how vaccine development has been progressing (worldwide) all year.
Robin McKie is The Observer's science editor, and he's done pretty good stuff about both climate change and (attacking) science-debunking, also about Covid, in the past months :cool:

Observer headline said:
The vaccine miracle: how scientists waged the battle against Covid-19
We trace the extraordinary research effort, from the discovery of the virus’s structure to the start of inoculations this week

Most of the article is about the 2020 history of it all :), but towards the end we then get this :
Immunology expert said:
“In a way I am surprised that is has all gone so smoothly so far,” said Eleanor Riley, professor of immunology at Edinburgh University. “Normally, when you’re launching a new vaccine, you expect something, at some point, not to pan out as expected. However, things have moved forward seamlessly – which is great.”

Robin McKie said:
Nevertheless, a number of key concerns still have to be resolved. None of the early vaccines have demonstrated an ability to reduce the spread of the disease within a population. Vaccinated people, while protected against severe symptoms, could still transmit infection to others and that is a crucial issue, said Riley ... “If we want to have a Covid-free future, then we need something that really suppresses transmission. If not, then the virus will circulate non-stop and anybody who has not been vaccinated is always going to be at risk. In the short term it is not a problem. We just need to save lives. But in the longer term it will be an issue.”
Although .....

One encouraging hint has been provided by the Oxford-AstraZeneca vaccine. During its trials, participants were routinely tested to see if those getting the vaccine had lower viral loads in their throats and noses than those who got the placebo. Early signs suggested they did have lower loads and may therefore be less likely to transmit the virus. “I think it would be surprising if the vaccines we have got already did not limit transmission in some way,” added Riley. “We should find out soon.”

:) :cool:
 
Back
Top Bottom