Results demonstrated vaccine efficacy of 76% (CI: 59% to 86%) after a first dose,
Note that, if I'm remembering correctly, efficacy in the context of this study means reducing transmission. In the context of preventing people getting serious C19 and ending up in hospital (which was the overwhelming crisis that was fast approaching with hospitals starting to run out of capacity), efficacy of the AZ appears to be much, much higher - at least 90% and possibly nearly 100%. Time will tell, but it was the right decision to start putting AZ in to as many arms as possible as soon as possible. Whilst there wasn't any complete academic study on this exact scenario, the preliminary data gave a strong suggestion that it was the case, so the scientists took a slight gamble, convinced the government of the gamble, and as a whole we and the NHS can all breathe a bit easier, both literally and metaphorically. Most medical staff in the UK TTBOMK have been prioritised to get the pfizer vaccine since it appears to give better transmission protection (but again it's going to be a long time before we know the full story).
Personally I'm currently of the opinion that we've had a lucky escape but that it's a largely orthogonal issue to brexit, but because they happen at the same time it's difficult to separate the two completely. The EU sabre-rattling over their own poor planning and logistics is at best childish and at worst downright ugly; the recent spats about the AZ vaccine reek of panicked face-saving (since you had almost all of the continental medical authorities saying that even if AZ
did cause blood clotting, C19 causes clotting anyway* and is far more deadly... so take the fuckin' vaccine!) which has poured diesel on to an already toasty tyre fire, and dropping this particular political bollock is going to result in thousands more deaths. As I mentioned in another thread the press in italy has whipped up a massive storm and convinced lots of mugwumps to panic and swear off any vaccines at all, ever. My partner's mother, 65, has been told she can expect to be able to book for her (pfizer) vaccine appointment in
seven months. There's certainly a technocratic side to the EU here that appears to have blundered substantially, in a similar way to our own home-grown substantially blundering technocrats were doing a year ago, and both are eyeing each up as Aunt Sally whilst the science and healthcare folk roll their eyes in despair**.
Anyway, this is all probably more relevant for the C19 board than the usual pram-throwing that goes on in this thread. I voted remoaniac and I'm still convinced brexit is a cake made of foetid pig effluent with union jack icing and a bulldog artfully placed on top for our dining pleasure (not eating your slice is not an option and no, you can't have a corner bit with slightly less pig shit in it). One accidental victory with vaccines at the same time as an EU mis-step isn't going to make up for all the other disruption going on at the same time (particularly with trade which is getting very ugly very quickly), but as long as brexit and C19 are happening at the same time, many people will ascribe all deleterious effects to their demon of choice and all advantages to their preferred messiah, because that's the simple nuance-free option.
* For those interested, last I read was that the clotting was put down to people having an allergic reaction to their own antibodies produced by their own bodies' immune response, so it can happen with any vaccine (and had already been recorded with the pfizer one at least) and of course
would also happen if you caught C19, giving you a double-whammy. In most studies, the incidence of blood clots in AZ recipients is lower than the general population; the strongest data to the contrary is currently coming out of Norway
who release their further findings on the matter tomorrow.
** Bias on my part here because I (laughably) consider myself a scientist and have been rolling my eyes so much over the last year I've given myself a crick in the neck.