Explain what?
I thought the use of these drugs for precocious puberty was common knowledge. Has certainly been discussed on these boards plenty.
This doesn’t mean they were deemed safe, either. They were used initially off-label (which is different to being “prescribed normally”) after careful consideration of the balance of risks. I think later licensing may have been patchy. There was also some occasional use on unusually small children to allow them to “catch up” before hitting puberty (which then determines the final height they may reach). There has been a little controversy about this.
Studies from the US have shown that between 20-40% of prescriptions are off label and the figure is even higher in paediatric medecine so it is normal. Puberty blockers being used to allow kids to grow taller was actually pretty commonplace but is rarer now. Precocious puberty can be a sign of an underlying problem but the main dangers are psychological distress (much like with trans kids), it does not usually carry physical health risks. The follow up and ongoing studies of puberty blockers used in trans healthcare have not identified any problems and even Cass could not find any evidence of harm.
There are lots of areas of paediatric medicine that are controversial or which may cause long term effects - the widespread use of SSRIs and anti-psychotics being two examples and these are used far more commonly than the tiny number of kids being proscribed blockers. And yet no other area of treatment has been subject to this kind of scrutiny and blanket bans which fly in the face of all expert opinion and are not supported by any evidence of harm.