The whooping cough vaccine scare in the 1970s went way beyond what we've seen with modern anti-vax stuff.
In countries including the UK it caused vaccination rates for whooping cough to fall by a really massive amount, perhaps as significant as uptake of that vaccine falling down from a high of getting on for 80% all the way down to under 40% uptake over a short number of years! This then led to several really major epidemics, because the population immunity picture had been badly compromised in age groups likely to spread it, before vaccine uptake rates later recovered at some point in the 1980s.
The scare included some doctors thinking there was a link between that vaccine and brain damage. There was no internet to spread the FUD, but there was also no internet to help people to get all the available facts and sense of perspective.
It was this scare that led to governments such as the UKs actually introducing a vaccine compensation scheme, as part of responding to public demands and trying to restore confidence.
The recovery of public confidence in that vaccine was probably a combination of studies that eventually reported, which showed no confirmed link between the vaccine and the brain damage (which would have also influenced doctors fears), epidemics leading to heightened public awareness of the dangers of the disease the vaccine had prevented, and the vaccine injury compensation scheme that was setup.
Public concern was understandable given the info that was floating around, and the establishment were slow to find a way of coping with such concerns. And the attitude of a families own GP had an impact at the time. I wasnt vaccinated because our GP advised caution in response to parental concerns, and I remember both myself and my younger brother catching the whooping cough as a result, probably in one of those epidemic years. It wasnt very pleasant. And my parent were not in any way anti-vaccine more broadly, I had every other standard jab at the right age.
That scare became a textbook lesson in how to do better at anticipating and mitigating losses of confidence in vaccination programmes. Various papers exist online about this stuff, eg:
Pertussis - Vaccinating Britain - NCBI Bookshelf