Cross-cutting themes for action to end COVID-19 as a public health threat
SARS-CoV-2 still moves among us - despite some governments moving on - requiring continued efforts and resources to save lives. Reservoirs exist from which variants of concern may yet emerge; possible endemicity does not necessarily mean lower disease severity. Broad-based funding to develop long-lasting immunogenic vaccines must proceed concurrent with other prevention measures. The long-term impact of infection must be assessed, as long COVID has emerged as a chronic condition.
Vaccines are an effective tool against COVID-19 but will not alone end COVID-19 as a public health threat. Vaccination as a sole pandemic response strategy has limitations due to immune escape, waning immunity, inequitable access, vaccine hesitancy and the absence of immunization strategies. A multifaceted public health vaccines-plus approach is needed, including testing, surveillance, treatment, community engagement and implementation of social prevention measures (such as facemasks, distancing and quarantine), structural interventions (such as ventilation and air filtration) and financial incentives (for example, support measures).
Multisectoral collaboration that centres on communities and fosters trust is needed. Ending COVID-19 as a public health threat requires whole-of-society and whole-of-government approaches engaging trusted community leaders and organizations, scientific experts, businesses, and other disciplines and sectors. This expanded pool of collaborators can best address diverse needs regarding modes of access, communication, innovation and trust among different populations.
Responsive health systems are crucial for responding to the COVID-19 pandemic and require coordinated government support. The persistent demand on health systems requires protecting the physical and mental wellbeing of healthcare workers; reducing economic barriers for equipment and treatment, including addressing supply-chain factors; strengthening primary care; and adopting a comprehensive, intersectoral, multilevel approach to preparedness and response activities.
Adverse forces challenge efforts to end the COVID-19 public health threat. Counteract sovereign state actors who are openly antagonistic toward science and public health and other entities with vested interests that disseminate false information. Public health authorities should build trust in evidence-based communications and partner with those monitoring and holding accountable disseminators of false information.
None of us is safe until everyone is safe. Pandemic inequities must end. This includes taking into account pre-existing social determinants of health, addressing access to affordable vaccines, tests, other supplies and treatment, and paying special attention to the needs of vulnerable groups (such as older and immunocompromized individuals, children and healthcare workers).