Anyway, can jumping on your lap and purring any opportunity they get be a sign of feeling unwell and wanting comfort, or is it just a sign of growing older? Trillian has a little nodule which is probably nothing but could be a sign of a hyperactive thyroid. It’s hard to tell if she’s more hungry as she’s always been a greedy guts. She might have lost weight but I’m trying to hold out another month before a re-weighing at the vets to give a clearer picture. One of my childhood cats had an overactive thyroid and I mainly remember the constant meowing.