Have you caught Covid recently - updated poll 2022-23

[~ Cyber Geek ~]

Post-COVID immune dysregulation is an area of ongoing research, though often focused on issues around autoimmunity:

Autoimmunity and Immune Dysregulation in Long COVID - RTHM

The SARS-CoV-2 virus may be causing confusion within the body's immune system. To learn more about this immune dysregulation, visit RTHM.

rthm.com

However, some studies already point to reactivation of various latent viruses in SARS-CoV-2 convalescents (eg DOI:10.3389/fimmu.2022.949787), which could be considered a contribution to PASC.

The apparent ability of recent omicron lineage variants to down-regulate various aspects of innate immunity (eg DOI:10.1101/2022.07.12.499603) may also perhaps play a role here.


Widely available RAT overwhelmingly focus on nucleocapsid antigen, structural proteins, which tend to be largely invariant: specificity hasn't changed much. However sensitivity has - populations have much higher levels of acquired immunity and lower viral loads, with commensurate reduced peak window sampling sizes.


Whole genome or next generation Sanger sequencing are exactly how new variants are discovered. Whilst these methods have predominately used amplicons from nasopharyngeal SARS-CoV-2 RT-PCR testing, test samples can just as easily, actually even more easily, be obtained via other routes. For example, wastewater sampling (sewerage treatment facilities, aircraft toilets) is increasingly flagging up crypto-variant (and potential zoonotic) development well ahead of clear signals in the primary healthcare system.

Interesting about wastewater. We learn something new everyday

 

[editor]

Oh you’re teasing whoops i misunderstood
I just invented a username before

Oh and also I told editor that his username suits him for a dictator... admin

Permabanned.

 

[ska invita]

.

 

[wemakeyousoundb]

tested negative just now, so apart from the initial feelings of being about to be unwell and some dodgy guts on day 2 and 3 absolutely no other symptoms for me.

 

[May Kasahara]

11 days on from when I first started to feel ill, I am pretty much recovered - coughing has reduced to minimal, still loads of snot but nothing abnormal for January. I am noticeably more tired and breathless though. Taking it very easy, physically.

 

[wtfftw]

Positive test this morning. In bed with a raised temp now.

 

[cesare]

Positive test this morning. In bed with a raised temp now.

GWS x

 

[May Kasahara]

Feel better soon wtfftw

 

[Agent Sparrow]

Glad you’re on the mend May Kasahara but being careful to take things slowing, and hope you don’t feel too awful and recover quickly wtfftw .

Don’t know about how other parents/people in regular close contact with kids feel, but I’m feeling quite resigned to this being an annual thing now

 

[Riklet]

Almost negative, the most invisible of a positive line today. I don't think most people would even notice. But it's def a positive. Feeling much more normal but not amazing. Still got this tight horrible jaw that started before the covid with this recent cold/virus.

Undecided about whether to work from home despite feeling run down still or just call in sick again. Obviously my baseline was long covid and not yet recovered from a nasty cold so not 100% by any means. I really dont feel like driving into the office next week so hopefully I can get out of that at least....

 

[MBV]

I'm still testing positive which means I'm cancelling my day in the office tomorrow. I don't feel particularly unwell at least.

 

[wtfftw]

Positive test this morning. In bed with a raised temp now.

Negative test
Still feeling pretty crappy so will take it as easy as possible.

 

[lazythursday]

Came down with cold on Sunday, spent all day on sofa. A lot better yesterday, but decided to test as was planning to visit elderly mother this week and much to my surprise a strong positive. So my second infection, the first around a year ago. Fully vaxxed, last boosted in November. And on strike this week so can't even take advantage of a few days sick, meh.

 

[kalidarkone]

Popped my covid cherry at last!
I was feeling guilty for not going to work today as I'm not really unwell......

 

[girasol]

This winter was definitely much better than the last, when we had to miss Christmas with family as I had (mild but detectable) covid. This time around I got away with not really getting ill at all. I think I felt under the weather a couple of times for a day. Once again I got both covid and flu jabs.

 

[kalidarkone]

It's just like having a bad cold but with extreme itchiness and abdominal pain/ loose stools. Slightly different symptom each day. The lines on the LFT are much more prominent then before.

 

[2hats]

Involuntarily conducted my own, personal (N=1), non-randomised challenge trial: I spent 3 days in the very close company of someone with mild classic symptoms, who tested positive at the end of that period. So right in the peak window of any infectious viral shedding (variant most probably one of BQ.1/BA.2.75/XBB[.1.5]/BA.5, in order of decreasing likelihood). They attended events/office in the 36 hours beforehand and likely picked it up there or during associated use of public transport (which nicely fits the typical omicron-lineage infection cycle).

They quadruple jabbed (heterogenous with longer booster spacing interval; last one bivalent) with no prior infection, me with hybrid immunity (1st wave infection only) and three jabs (all adequately spaced for maturation, ie >7 months; all monovalent, mix of mRNA).

I had no symptoms and no positive tests at any point from days 1 through to 17 after 'exposure' (at which point I gave up testing) and then no symptoms since (at 1 month any apparent infection, symptoms or positive test, would now be more likely to have come from a subsequent exposure).

I would guess a combination of vaccination regime reducing the source infectious viral shedding window/load and target hybrid immunity with adequate maturation timing and mucosal IgA response perhaps avoiding or rapidly aborting any infection.

So, in answer to the OP, nope.

 

[kalidarkone]

Today I feel as though I have completely recovered, aside from an annoying cough and feeling of something needing to be coughed up.

I'm still testing positive and cannot go back to work till next week at the earliest. If still testing positive but not unwell I can return after day 14.

 

[Riklet]

Today I feel as though I have completely recovered, aside from an annoying cough and feeling of something needing to be coughed up.

I'm still testing positive and cannot go back to work till next week at the earliest. If still testing positive but not unwell I can return after day 14.

Just take it easy and rest for a few days because things go up and down with Covid.

My workmate felt better then got worse again and was off for 5 more days just recently.

 

[kalidarkone]

Just take it easy and rest for a few days because things go up and down with Covid.

My workmate felt better then got worse again and was off for 5 more days just recently.

I won't really properly know how it's affected me till I'm out of isolation and walking around outside.

 

[kalidarkone]

So day 8/9 still testing positive. ( I know one can test positive for up to 90 days after having had covid) completely well- infact I feel really good! Although as stated above I won't really know till I'm back to doing my usual tasks.

Is it OK to go out?

 

[Miss-Shelf]

So day 8/9 still testing positive. ( I know one can test positive for up to 90 days after having had covid) completely well- infact I feel really good! Although as stated above I won't really know till I'm back to doing my usual tasks.

Is it OK to go out?

Yes
#notadoctor

 

[2hats]

So day 8/9 still testing positive. ( I know one can test positive for up to 90 days after having had covid) completely well- infact I feel really good! Although as stated above I won't really know till I'm back to doing my usual tasks.

Is it OK to go out?

By around day 10, for an immunocompetent vaccinee, most likely ok. If I worked/lived with or otherwise cared for or encountered clinically vulnerable people then I would mask up for them for another ~5 days (actually, if they were clinically extremely vulnerable I would likely mask around them all the time if any of my other associates were lax in their attitudes towards respiratory health).

Isolation

COVID-19 isolation recommendations if you are sick.

www.cdc.gov

 

[kalidarkone]

By around day 10, for an immunocompetent vaccinee, most likely ok. If I worked/lived with or otherwise cared for or encountered clinically vulnerable people then I would mask up for them for another ~5 days (actually, if they were clinically extremely vulnerable I would likely mask around them all the time if any of my other associates were lax in their attitudes towards respiratory health).

Isolation

COVID-19 isolation recommendations if you are sick.

www.cdc.gov

I'm not permitted to return to work until I have had 2 negative LFTs before this Friday (day 10) or 1 negative LFT before the following Tuesday (day 14) and yes will continue to wear a mask at work.

 

[RD2003]

It's getting weird now. Due to circumstances, I, along with most others I regularly associate with, have thrown all caution to the winds over the last 6-9 months, except for where strictly required-masks and tests when visiting care homes and so on-and personally not even a cold to speak of. I'm sure I regularly used to get more viruses before Covid. And yet you hear of people who have picked up Covid yet again despite having had the 4 vaccine doses like me.

Having said that, I'll probably appear on here posting about my second and worse bout of Covid some time soon.

 

[kalidarkone]

It's getting weird now. Due to circumstances, I, along with most others I regularly associate with, have thrown all caution to the winds over the last 6-9 months, except for where strictly required-masks and tests when visiting care homes and so on-and personally not even a cold to speak of. I'm sure I regularly used to get more viruses before Covid. And yet you hear of people who have picked up Covid yet again despite having had the 4 vaccine doses like me.

Having said that, I'll probably appear on here posting about my second and worse bout of Covid some time soon.

What's weird about it? People are very different is all. I like you have been out living my life, gigs, clubs, parties and front line NHS to boot. I finally picked it up last week- pretty mildly.
However I know people that despite being vaccinated have had it four times. They are the same people that got swine flu really badly and are always knocked for 6 every winter with chest infections etc.

 

[klang]

However I know people that despite being vaccinated have had it four times.

despite fully vacced and very careful, I caught it 3 times in 1 year. Twice mildly, once badly.

 

[klang]

...and I'm generally a healthy person and don't usually catch whatever illness is floating about at any given time.

 

[Jennaonthebeach]

contrary to how i voted here a few weeks ago, I have now had it.

 

[RD2003]

What's weird about it? People are very different is all. I like you have been out living my life, gigs, clubs, parties and front line NHS to boot. I finally picked it up last week- pretty mildly.
However I know people that despite being vaccinated have had it four times. They are the same people that got swine flu really badly and are always knocked for 6 every winter with chest infections etc.

Weird in the sense that in contrast to lately I was still being fairly careful when I picked it up early last summer, I suppose. Also, others I know who are the type you mention, normally catching everything going, haven't been getting it recently either despite lack of any workplace precautions and being back to pre-Covid routines and activities.