Ninian Park is braced for a top-of-the-table encounter as Wolves travel to Cardiff.
The Bluebirds currently sit third, well-placed to launch an automatic promotion bid after suffering just one defeat in 14 games.
Wolves, though, lead the way in the Championship and will be looking to consolidate their place at the summit.
Cardiff team news
Peter Whittingham is pushing for a recall to Cardiff's starting XI after his goalscoring exploits in midweek against Blackpool.
The midfielder has failed to start the last two games but came off the bench against the Seasiders on Tuesday night to net the crucial 83rd-minute opener.
Defender Miguel Comminges or midfielder Paul Parry are likely to be the player to make way if boss Dave Jones decides to switch things around against his former club.
Captain Darren Purse, midfielders Stephen McPhail and Joe Ledley and striker Jay Bothroyd shook off knocks in time to start on Tuesday and all are expected to feature as the Bluebirds look to pick up three crucial points against their promotion rivals.
However, Mark Kennedy is likely to miss out again and fellow midfielders Riccardo Scimeca (groin) and Tony Capaldi (knee) also face further time on the sidelines.