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Covid hides in a lipid (fatty bubble) within a cell, the ability to detect the virus depends on an OAS1 enzyme with a fatty tail

HAL9000

Well-Known Member
Covid hides in a lipid (fatty bubble) within a cell, if a cell is a room, covid creates another room within the cell to hide inside.

The ability to detect this virus inside a lipid depends on if the immune system has an OAS1 enzyme with a fatty tail (technical word is Prenylated). With a tail, its good at detecting the virus, no tail, bad at detecting the virus.

Looking at intensive care patients with covid19. Those that had the OAS1 molecule without a fatty tail, this was associated with more severe disease. So there might be genetic factor which determines the outcome.

I know very little about biology, details are in this radio program...


7 minutes 52 seconds to 17 minutes 18 seconds

the paper they are discussing is called "A Prenylated dsRNA Sensor Protects Against Severe COVID-19 and is Absent in Horseshoe Bats"
 
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