Got by another spam email-checking I will be ok
- Thread starter panpete
- Start date
panpete
Blokes name, birds body.
thanks
Epona
Sonic: 1 Nov 2006 - 8 Jan 2022
I mean it is bollocks, sleeping in any particular position is not a sign that you will develop dementia
But if you didn't give them any personal or bank details then probably alright.
Don't click on links that are sent to you though!!! Unless you know 100% who they are from and what it is about, just don't.
But if you didn't give them any personal or bank details then probably alright.
Don't click on links that are sent to you though!!! Unless you know 100% who they are from and what it is about, just don't.
story
Changing the facts
Actually....
Recent discovery of the lymphatic system in the brain....
Brain’s Fluid Drains via Lymphatic Vessels at the Base of the Skull
Detailed imaging of the rodent central nervous system reveals new information about the route cerebrospinal fluid takes to leave the brain.
www.the-scientist.com
....Led to further research that strongly suggests a correlation between poor lymphatic drainage from the brain lymphatic system and Alzheimer’s in mice....
Boosting brain’s waste removal system could improve Alzheimer’s outcomes
A study in mice showed that antibody therapies targeting amyloid-beta protein were more effective after enhancing the brain’s waste drainage system.
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
www.frontiersin.org
.... and further studies seem to show the same thing is also possible in humans.....
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
www.frontiersin.org
...that this system - the glymphatic system - is more active at night and less active during the day....
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
www.ncbi.nlm.nih.gov
.....and also that the position we sleep in seems to have an effect on the efficacy of the glymphatic system
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
www.ncbi.nlm.nih.gov
The Effect of Body Posture on Brain Glymphatic Transport
The glymphatic pathway expedites clearance of waste, including soluble amyloid β (Aβ) from the brain. Transport through this pathway is controlled by the brain's arousal level because, during sleep or anesthesia, the brain's interstitial ...
www.ncbi.nlm.nih.gov
Could body posture during sleep affect how your brain clears waste?
Sleeping in the side position, as compared to on one’s back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer’s and other neurological diseases, new research suggests.
www.sciencedaily.com
On Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALS - Neuroscience News
A new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.
neurosciencenews.com
None of this is cast iron nailed down fact yet but it looks
Those click bait articles are just trying to pull people in and best avoided. But the theory behind the story does appear to be fairly sound.
Whether or not we develop dementia is obviously multifactorial and not caused by the position we sleep in. However, It does look as if there is some correlation, at least in animal studies, between effective lymphatic clearance of the brain and increased risk of dementia and other neurological problems. And it does look as if the brain cleans itself better when we sleep in certain positions than in others.
Caveats etc
I’m not a research scientist I’m not a neurologist and I don’t have any specialist knowledge about dementia. But I do read science papers. This is a story that has interested me for a long time. I think it’s really interesting.
But yeah, panpete don't click on stuff that’s trying to sell stuff. If something piques your interest, do a separate Google search to find out more about whatever it is, don’t click through on the stuff that lands in your inbox.
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Epona
Sonic: 1 Nov 2006 - 8 Jan 2022
Actually....
Recent discovery of the lymphatic system in the brain....
Brain’s Fluid Drains via Lymphatic Vessels at the Base of the Skull
Detailed imaging of the rodent central nervous system reveals new information about the route cerebrospinal fluid takes to leave the brain.
....Led to further research that strongly suggests a correlation between poor lymphatic drainage from the brain lymphatic system and Alzheimer’s in mice....
Boosting brain’s waste removal system could improve Alzheimer’s outcomes
A study in mice showed that antibody therapies targeting amyloid-beta protein were more effective after enhancing the brain’s waste drainage system.www.nih.gov
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
.... and further studies seem to show the same thing is also possible in humans.....
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
...that this system - the glymphatic system - is more active at night and less active during the day....
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
.....and also that the position we sleep in seems to have an effect on the efficacy of the glymphatic system
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
The Effect of Body Posture on Brain Glymphatic Transport
The glymphatic pathway expedites clearance of waste, including soluble amyloid β (Aβ) from the brain. Transport through this pathway is controlled by the brain's arousal level because, during sleep or anesthesia, the brain's interstitial ...
Could body posture during sleep affect how your brain clears waste?
Sleeping in the side position, as compared to on one’s back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer’s and other neurological diseases, new research suggests.www.sciencedaily.com
On Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALS - Neuroscience News
A new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.
None of this is cast iron nailed down fact yet but it looks pretty certain. So far most studies are in animals, and the findings are still so recent that we’ve not been able to observe anything long term in humans.
Those click bait articles are just trying to pull people in and best avoided. But the theory behind the story does appear to be fairly sound.
I have enough trouble getting to sleep as it is
story
Changing the facts
I have enough trouble getting to sleep as it is
Never mind mate, any minute now someone will come along to say I’m posting up dangerous bullshit and how it’s not true and you can confidently go ahead and dismiss all that information and stop worrying.
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platinumsage
HaveMyPassword123
Indeed, it's a study done on anesthetized mice. It really can't be applied to humans at all, so definitely not worth worrying about. The authors of the study even admit that it's total speculation, and say that a first step in working out if any particular sleeping position has an effect in humans is to do a study on humans. A human study could easily find the opposite to be true, so it's really not a basis for making decisions.
story
Changing the facts
As I pointed out more than once in the paragraphs preceding the one you quoted.
But it’s not just one study. This is a pretty broad area of research, albeit mostly in animals at the moment. But there is some extraploation to humans as well as some human studies and it looks like there’s could be something in it.
Head Position During Sleep: Potential Implications for Patients with Neurodegenerative Disease
The characterization of sleep in those with neurodegenerative disease (NDD) is essential in understanding the potential neurobiological mechanisms that underlie the connection between sleep disruption and NDD manifestations and progression. Explore the ...
www.ncbi.nlm.nih.gov
Could Your Sleep Position Help Reduce Alzheimer's Risk? - Neuroscience News
According to a new study, sleeping on your side helps the clear the brain of some neurotoxins, like amyloid beta, and could potentially reduce risk for developing some neurodegenerative disorders.
neurosciencenews.com
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PubMed
The glymphatic system is a "pseudo-lymphatic" perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport in which harmful interstitial metabolic waste products...
pubmed.ncbi.nlm.nih.gov
Glymphatic MRI in idiopathic normal pressure hydrocephalus - PubMed
The glymphatic system has in previous studies been shown as fundamental to clearance of waste metabolites from the brain interstitial space, and is proposed to be instrumental in normal ageing and brain pathology such as Alzheimer's disease and brain trauma. Assessment of glymphatic function...
pubmed.ncbi.nlm.nih.gov
Head Position During Sleep: Potential Implications for Patients with Neurodegenerative Disease - PubMed
This study demonstrates the utility of in-home measurements of sleep in defining the association of supine sleep position with neurodegenerative disorders. Our findings warrant further investigation, particularly in light of the recent evidence suggesting that sleep may an active role in the...
pubmed.ncbi.nlm.nih.gov
I realise that some people automatically dismiss anything and everything I say about health but there’s a risk when doing so that something interesting and potentially useful gets tossed out too.
I’m NOT saying that the the position we sleep in causes or protects us from dementia etc. I’m only saying that it looks as if there COULD be some some evidence that the position we sleep in MIGHT help our brain to stay healthy.
Obviously, obviously it’s a whole set of complicated and probably interrelated factors that ends up leading to Alzheimer’s. I’m not saying anything to the contrary. I’m saying that it looks as if POSSIBLY one of those factors MAY be inadequate clearance/cleaning of the brain’s lymphatic system. And it looks as if that happens at night, and POSSIBLY when the head and body is in an optimal position for that to occur. I’m not inventing this, I’m taking it from science papers. I had no idea, no clue, no notion about this until I read it. It doesn’t come from my imagination.
platinumsage
HaveMyPassword123
As I pointed out more than once in the paragraphs preceding the one you quoted.
But it’s not just one study. This is a pretty broad area of research, albeit mostly in animals at the moment. But there is some extraploation to humans as well as some human studies and it looks like there’s could be something in it.
Head Position During Sleep: Potential Implications for Patients with Neurodegenerative Disease
The characterization of sleep in those with neurodegenerative disease (NDD) is essential in understanding the potential neurobiological mechanisms that underlie the connection between sleep disruption and NDD manifestations and progression. Explore the ...
Could Your Sleep Position Help Reduce Alzheimer's Risk? - Neuroscience News
According to a new study, sleeping on your side helps the clear the brain of some neurotoxins, like amyloid beta, and could potentially reduce risk for developing some neurodegenerative disorders.
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices - PubMed
The glymphatic system is a "pseudo-lymphatic" perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport in which harmful interstitial metabolic waste products...Glymphatic MRI in idiopathic normal pressure hydrocephalus - PubMed
The glymphatic system has in previous studies been shown as fundamental to clearance of waste metabolites from the brain interstitial space, and is proposed to be instrumental in normal ageing and brain pathology such as Alzheimer's disease and brain trauma. Assessment of glymphatic function...Head Position During Sleep: Potential Implications for Patients with Neurodegenerative Disease - PubMed
This study demonstrates the utility of in-home measurements of sleep in defining the association of supine sleep position with neurodegenerative disorders. Our findings warrant further investigation, particularly in light of the recent evidence suggesting that sleep may an active role in the...
I realise that some people automatically dismiss anything and everything I say about health but there’s a risk when doing so that something interesting and potentially useful gets tossed out too.
I’m NOT saying that the the position we sleep in causes or protects us from dementia etc. I’m only saying that it looks as if there COULD be some some evidence that the position we sleep in MIGHT help our brain to stay healthy.
Obviously, obviously it’s a whole set of complicated and probably interrelated factors that ends up leading to Alzheimer’s. I’m not saying anything to the contrary. I’m saying that it looks as if POSSIBLY one of those factors MAY be inadequate clearance/cleaning of the brain’s lymphatic system. And it looks as if that happens at night, and POSSIBLY when the head and body is in an optimal position for that to occur. I’m not inventing this, I’m taking it from science papers. I had no idea, no clue, no notion about this until I read it. It doesn’t come from my imagination.
You said “it looks pretty certain” and “it does look as if the brain cleans itself better when we sleep in certain positions than in others”, but neither statement is supported by the links you’ve posted.
story
Changing the facts
Okay I’ll go back and edit the “pretty certain” bit.
But to my reading, it does look like those studies do support the hypothesis that the brain cleans itself more effectively when the head is in a certain position during sleep. If the head is in a certain position when we sleep, so too is the rest of the body. So I’ll leave that in and say it’s my opinion based on what I’ve read and not established fact.
To clarify.
It is my opinion that the studies I’ve read support the idea that the position we sleep in MIGHT enhance the glylymphatic drainage of the brain and thus COULD contribute to reduced incidence of some causative factors that may contribute to the development of NND in animals and possibly humans too.
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platinumsage
HaveMyPassword123
I mean it's an interesting theory but no more than that. Certainly not something that should cause anyone to start changing their sleep habits.
story
Changing the facts
Never said it was.
The studies do suggest there may be benefits for those who do sleep on their side. But obviously obviously very clearly and obviously that’s not going to be the magic thing that eliminates dementia. And obviously obviously very clearly and obviously sleeping in any other position is not dangerous and doesn’t cause Alzheimer’s.
And obviously obviously very clearly and obviously those click bait articles that claim to be based in science are scammy bullshit.
panpete
Blokes name, birds body.
I could kick myself for not looking at the address it was sent from, otherwise, like you say, do not click on the link. I agree that it is bollocks.
panpete
Blokes name, birds body.
It is a lesson for me to always look at the address it is sent from because spam emails always look like dodgy addresses. I had a quick look through your post, but did not read at all, that's just because I am lazy when it comes to scientific research.Actually....
Recent discovery of the lymphatic system in the brain....
Brain’s Fluid Drains via Lymphatic Vessels at the Base of the Skull
Detailed imaging of the rodent central nervous system reveals new information about the route cerebrospinal fluid takes to leave the brain.
....Led to further research that strongly suggests a correlation between poor lymphatic drainage from the brain lymphatic system and Alzheimer’s in mice....
Boosting brain’s waste removal system could improve Alzheimer’s outcomes
A study in mice showed that antibody therapies targeting amyloid-beta protein were more effective after enhancing the brain’s waste drainage system.
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
.... and further studies seem to show the same thing is also possible in humans.....
Frontiers | Research on the Glial–Lymphatic System and Its Relationship With Alzheimer’s Disease
Metabolic waste clearance is essential to maintain body homeostasis, in which the lymphatic system plays a vital role. Conversely, in recent years, studies h...
...that this system - the glymphatic system - is more active at night and less active during the day....
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
.....and also that the position we sleep in seems to have an effect on the efficacy of the glymphatic system
The Sleeping Brain: Harnessing the Power of the Glymphatic System through Lifestyle Choices
The glymphatic system is a “pseudo-lymphatic” perivascular network distributed throughout the brain, responsible for replenishing as well as cleansing the brain. Glymphatic clearance is the macroscopic process of convective fluid transport ...
The Effect of Body Posture on Brain Glymphatic Transport
The glymphatic pathway expedites clearance of waste, including soluble amyloid β (Aβ) from the brain. Transport through this pathway is controlled by the brain's arousal level because, during sleep or anesthesia, the brain's interstitial ...
Could body posture during sleep affect how your brain clears waste?
Sleeping in the side position, as compared to on one’s back or stomach, may more effectively remove brain waste and prove to be an important practice to help reduce the chances of developing Alzheimer’s and other neurological diseases, new research suggests.www.sciencedaily.com
On Your Back, Side, or Face-Down? How We Sleep May Trigger or Protect Our Brain From Diseases Like ALS - Neuroscience News
A new mouse study reveals our sleep position may influence the glymphatic system and could increase the risk of developing ALS or other neurodegenerative diseases.
None of this is cast iron nailed down fact yet but it lookspretty certainlike it could be possible. So far most studies are in animals, and the findings are still so recent that we’ve not been able to observe anything long term in humans.
Those click bait articles are just trying to pull people in and best avoided. But the theory behind the story does appear to be fairly sound.
Whether or not we develop dementia is obviously multifactorial and not caused by the position we sleep in. However, It does look as if there is some correlation, at least in animal studies, between effective lymphatic clearance of the brain and increased risk of dementia and other neurological problems. And it does look as if the brain cleans itself better when we sleep in certain positions than in others.
Caveats etc
I’m not a research scientist I’m not a neurologist and I don’t have any specialist knowledge about dementia. But I do read science papers. This is a story that has interested me for a long time. I think it’s really interesting.
But yeah, panpete don't click on stuff that’s trying to sell stuff. If something piques your interest, do a separate Google search to find out more about whatever it is, don’t click through on the stuff that lands in your inbox.
Epona
Sonic: 1 Nov 2006 - 8 Jan 2022
That sounds a bit like sleep paralysis (which a lot of people, myself included, get - and although it can be frightening at the time, it isn't at all harmful).
panpete
Blokes name, birds body.
My experience of sleep paralysis is not been able to move but yearning to I'm feeling scared. They holding my breath thing has just started in the last few years, but I had sleep paralysis much sooner before. I noticed sleep paralysis increase when I started using 5HTP.
Epona
Sonic: 1 Nov 2006 - 8 Jan 2022
Sleep paralysis can indeed take a form where it feels like you are struggling to breathe when you wake up - this is something that regularly affects me.
When you wake up in this state, try to look at something that you know is real (as hallucinations can also happen, so focus on something that you know is real like your bedside lamp, or a glass/bottle of water that you put there, or if you are laying on your back and cannot move focus on the bit of ceiling above you - something that is real.) Then count to yourself - 1, 2, 3.... you will not be in paralysis forever, or even for very long at all, counting makes it less panicky and reminds you that you are getting near the end of it and will be able to move soon.
Also if you feel you can't breathe, try to remember that you haven't stopped breathing, you are just at a slower rate of breathing that suits being asleep - although it is frightening that you can't breathe as deeply as you would when fully awake and are not in control of it, no harm will come to you and it will ease up probably after a minute, even though it can seem like an age when it is happening.
I understand how frightening sleep paralysis can be however.
panpete
Blokes name, birds body.
Thank you. Sorry it happens to you.
bmd
Island in the stream.
Nah, everyone gets caught out. Just be kind to yourself over stuff like this.
